He joined a football academy at the age of 12, where he drew attention of a scout who brought him to Internaples (the name of the club "Napoli" at the time).

Due to his background, Sallustro chose not to take any financial pay from the club, as his father believed that it was unacceptable to earn a living in such a manner.

[5] After retiring from football in 1939, following a two-year spell with Salernitana, he stayed in Naples until his death in 1983, serving as the director of the city's San Paolo Stadium between 1960 and 1981, Napoli's home ground, and as the club's manager in 1961.

[6] He made one start in the silver medal 1931–32 Central European International Cup campaign, in Italy's 3–0 win against Switzerland.

Despite his goal-scoring pedigree at club level, he was kept out of the side during much of his playing days due largely to the inclusion of Giuseppe Meazza in the centre-forward role by manager Vittorio Pozzo.