Moving to New Orleans, the couple's young daughter died of cholera in 1833 and was buried on the banks of the Mississippi.

[6][7] Facing difficulties in New Orleans as well, the Garretts separated for a short while - Augustus to Chicago, while Eliza returned to Newburgh.

In 1844, Garrett initially won re-election, only to have the election invalidated based on charges of "illegal proceedings and fraud.

[9] Augustus Garrett died at the Sherman House Hotel in Chicago on November 30, 1848, and was buried in Rosehill Cemetery.

[10] Following his death, Eliza established the Garrett Bible Institute, now Garrett-Evangelical Theological Seminary, in nearby Evanston, Illinois.