He played college football for the Western Colorado Mountaineers, finishing as their all-time leader in rushing yards before signing with the Los Angeles Chargers as an undrafted free agent in 2017.

[3] He was a four-year letterer and starter for the Fightin' Reds; despite being only 5 ft 5 in (1.65 m) as a freshman, Ekeler rushed for 454 yards and 8 touchdowns on 70 carries.

However, the first three universities wanted to switch him to the defensive side of the ball; Western Colorado was the only school to offer him at the tailback position.

[5] Ekeler attended and played college football at Western Colorado from 2013 to 2016 and is their all-time leader in rushing yards.

[12] In the season opening 24–21 loss to the Denver Broncos on Monday Night Football, Ekeler had two receptions for 18 yards in his NFL debut.

[18][19] In Week 14, against the Cincinnati Bengals, he aggravated a neck injury, which sidelined him for two games.

[25] Ekeler began the season as the starter while Melvin Gordon was in a contract dispute.

[33] He was the sixth player ever, and the first since Herschel Walker in 1986, to average over 10 yards per carry and reception in a 100/100 game.

[35] On March 16, 2020, Ekeler signed a four-year $24.5 million contract extension with the Chargers.

[37] In Week 3 against the Carolina Panthers, Ekeler recorded 143 yards from scrimmage and a rushing touchdown during the 21–16 loss.

[48] Ekeler, along with Colts running back Jonathan Taylor, led the NFL in touchdowns.

[62] In the regular season opener, Ekeler had 164 scrimmage yards and a rushing touchdown in the 36–34 loss to the Dolphins.

[67] In a Week 12 game against the Dallas Cowboys, Eleker suffered another concussion and was placed on injured reserve.

[76] Austin's biological father left the family at a young age and is currently serving a life sentence in a Nevada maximum security prison.

"[79] The same year he founded the Gridiron Gaming Group as a way for sports personalities to grow their online communities by livestreaming with other athletes.