The road is 3 lanes on both sides, being a part of the original Autopista A1, going from Havana to Santa Clara.

The motorway opened along with the Autopista Nacional, which it was originally a part of, before the A1 got continued until the town of Jatibonico.

It was part of construction efforts made after the Cuban Revolution in the city, along with the 26 de Julio Avenue, and the Santa Clara Beltway.

[1] In May 2018, the road was closed due to flooding and heavy rainfall, with drivers having to go around through the highway 4–112, to get to the Carretera Central, and then to the 4–474 on kilometer 270 of the A1.

[8] In April 2024, the Santa Clara Motorway had an operational closure for in order to "confront crime and illegalities.