Avigdor Yitzhaki (Hebrew: אביגדור יצחקי; born 13 September 1949) is an Israeli politician.

He is a former member of the Knesset for Kadima, having been the party's parliamentary group chairman and head of the coalition.

He is the chairman of Friends of Schneider.

On 2 May 2007, Yitzhaki requested that Prime Minister Ehud Olmert resign as soon as possible following the Winograd Commission's first report.

[1] On 7 February 2008 he resigned from the Knesset due to "serious doubts over Ehud Olmert's ability to lead the government in the wake of the Winograd Report".