Its 13 buildings are situated on a campus of 50 acres (20.2 ha) in Kansas City.

[3] In May 1961, Sister Mary Daniel Tammany, president of the College of St. Teresa, announced the purchase of 49 acres of land for a new campus at 119th and Wornall Road in the Red Bridge neighborhood near the southern edge of Kansas City, Missouri.

The high school, St. Teresa's Academy, is still operating on the original site.

Each College has a collection of Schools for the various programs: Avila's campus sits on 50 acres (20.2 ha) in southern Kansas City, Missouri.

The university is a member of the National Association of Intercollegiate Athletics (NAIA), primarily competing in the Kansas Collegiate Athletic Conference (KCAC) since the 2018–19 academic year.

In 2011, the athletic complex was expanded to provide facilities for football and soccer games to be played on campus.

A 194,000 square foot multi-purpose athletic field was constructed, featuring a Shaw Sportexe Legion synthetic turf system.

[12] Avila's football team played its first on campus game on September 17, 2011, against Missouri Valley College.