Axelrodichthys is an extinct genus of mawsoniid coelacanth from the Cretaceous of Africa, North and South America, and Europe.

[7] It differs from Mawsonia mainly in its more elongated parietonasal shield, the development of the descending process of the supratemporal, and by the shape and arrangement of the cheek and lower jaw bones.

Indeed, the Romualdo Formation, where this species mainly comes from, was deposited in a coastal lagoon influenced by cycles of marine transgressions and regressions and a variable supply of fresh water.

[9] At the end of the Upper Cretaceous, the species A. megadromos lived exclusively in fresh water (lakes and rivers), on the Ibero-Armorican island, an insular landmass made up of much of France and the Iberian Peninsula.

[21] A phylogenetic analysis of the mawsoniids published in 2020 found a polytomy grouping together the Cretaceous genera "Lualabaea", Axelrodichthys, and Mawsonia, as well as the Jurassic marine genus Trachymetopon.