Axolemma

[2] The skeletal framework of this structure is formed by a spectrum of hexagonal or pentagonal arrangement on the inside of the cell membrane, as well as actin connected to the transmembrane.

The metric cellular matrix is bound by transmembrane proteins, including the β1-integrin, to the cytoskeleton via the membrane skeleton.

These signals control the proliferative and myelin-producing functions of the Schwann Cells, and also partly play a role in the regulation of the size of the axon.

The transmembrane proteins keep the concentration of ions inside the cell and the concentration of ions outside the cell relatively balanced, with a net neutral charge, but if a difference in charge occurs right at the surface of the axolemma, either internally or externally, electrical signals, such as action potentials, can be generated.

However, repolarization overshoots the resting membrane potential, because the K+ channels experience a delay when closing, which causes a period of hyperpolarization.