Ayşe Işıl Karakaş (8 December 1958 – 24 January 2024) was a Turkish academic, professor of law, and former judge at the European Court of Human Rights in respect of the Republic of Turkey.

In 1983, she graduated from the Department of Political Science of Istanbul University, and between 1984 and 1993, she worked as a research assistant in the same institution.

In 1986, she gained her second master's degree in the field of European Law at the Centre Européen Universitaire at the Nancy II University.

In 1990, Karakaş graduated from the Faculty of Law of Marmara University, and was admitted to the Istanbul Bar Association in 1990.

She was a judge of the European Court of Human Rights in respect of the Republic of Turkey since 1 May 2008.