Ayourou is a department of the Tillabéri Region in Niger.

The department is located in the south-west of the country and borders Mali.

Its administrative seat is the city of Ayourou.

As a result of the conflict in northern Mali, the government of Niger declared a state of emergency in the department of Ayourou and six other departments in March 2017, which was subsequently extended several times.

[2] Ayourou Department is divided into two municipalities, listed with population as of 2012 census: