It is one of several sub-series in the Backyard Sports franchise and is the first to feature professional players as kids, examples being Steve Young and Barry Sanders.

[6] Brett Favre and Drew Bledsoe, who both appear in the first Backyard Football, return in this game, while Terrell Davis, Steve McNair, Jevon Kearse, Rich Gannon, Ricky Williams, Junior Seau, Donovan McNabb, and Cade McNown are added.

Donovan McNabb returns in this game, while Mike Vick, Jeff Garcia, Marshall Faulk, Curtis Martin, Marvin Harrison, Brian Urlacher, Jerome Bettis, David Boston, and Zach Thomas are added.

[10] Backyard Football 2006 was developed by Humongous Entertainment and published by Atari in 2005 for Windows, PlayStation 2, and Game Boy Advance.

Mike Vick, Donovan McNabb, Marvin Harrison, and Brian Urlacher return in this game, while Daunte Culpepper, Tom Brady, Matt Hasselback, Priest Holmes, LaDainian Tomlinson, Torry Holt, Peyton Manning, Michael Strahn, Tony Gonzalez, and Ahman Green are added.

[11] Backyard Sports Football 2007 was developed by Humongous Entertainment and published by Atari in 2006 for the Game Boy Advance.

Backyard Sports Football 2007 received negative reviews, being criticized for its repetitive sound and poor gameplay.

IGN rated the Wii version of the game a 6/10 and criticized it for having controls that may be hard for a younger audience to understand, while praising its commentary for being funny.

Professional players include Tom Brady, Peyton Manning, Tony Romo, LaDainian Tomlinson, Brian Urlacher, Reggie Bush, Chris Cooley and Frank Gore and more.

[19] Along with the NFL players, most of the classic backyard kids are in the game including Pete Wheeler, Pablo Sanchez, and Ernie Steele.

[20][21][22] Backyard Football '10 was also developed by the previous team who did the other two installments and published by Atari in 2009 for the Xbox 360, Wii, and PlayStation 2.

[26] Backyard Sports: Rookie Rush was developed by HB Studios and published by Atari in 2010 for the Xbox 360, Wii, Microsoft Windows, and Nintendo DS.