It rises in Newark Township near the city of Ithaca in Gratiot County and flows in a north-easterly direction into Saginaw County, and through the village of St. Charles, before emptying into the Shiawassee River within the bounds of the Shiawassee National Wildlife Refuge.

[4] The river and its tributaries have a total combined length of 175 miles (282 km); most of it channelized.

[4] Land use within the surrounding watershed is 86.5 percent agricultural; as a result, the river system has been adversely impacted by sedimentation.

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