Staff from Kew Gardens and the IRAD-National Herbarium of Cameroon worked on preparing an inventory of plants in the Kupe-Bakossi region between 1995 and 2005.

[2] The area is home to important large mammals that include the drill, African forest elephant, chimpanzee, and Preuss's red colobus.

[4] They are concentrated in the north and south of the park, perhaps due to greater availability of food and shelter and lower levels of hunting and farmland encroachment.

A field consultation program for gazettement of Bakossi National Park was completed in 2004, jointly supported by the World Wildlife Fund's Coastal Forests Programme and the San Diego Zoo's Center for Conservation and Research for Endangered Species.

[1] The signature followed shortly after the December 2007 release of the film "The Mists of Mwanenguba", which documents the importance of conservation in the Bakossi mountains.

[8] A 2011 report noted that outstanding tasks included completing the establishment process, demarcating boundaries and finalizing the management plan.

The indigenous people practice logging on a small scale, with the wood used for construction of homes and for making furniture, and harvest forest plants.

They cultivate cocoa and coffee as cash crops and grow plantain, cocoyam, cassava, beans and pepper for their own consumption and for sale.

Sacred forests and groves in the national park have significantly higher plant species diversity than in nearby Mount Cameroon.

[11] As of 2011 a project was being planned to convert over 70,000 hectares (270 sq mi) of unprotected land in the region into oil palm plantations.

Concerns are that clearance of forests to make way for the plantations will seriously affect the livelihood of the local people who depend on forest products, and that a massive influx of low-paid plantation workers will result in a sharp and unsustainable rise in illegal logging and hunting in protected areas such as the Bakossi National Park.

[15] Herakles has said "the plantations will follow the highest environmental and social standards, complying fully with Roundtable on Sustainable Palm Oil (RSPO) Principles & Criteria".