Baldassare Cenci, seniore (1648–1709) was a Roman Catholic cardinal.

Baldassare Cenci was born in 1648 in Rome, the youngest and fifth child of Virginio Cenci and Maria Vittoria Verospi.

[1] His nephew is cardinal Baldassare Cenci (iuniore).

[1] On 30 September 1691 he was consecrated bishop by Fabrizio Spada, Cardinal-Priest of San Crisogono, with Ercole Visconti, Titular Archbishop of Tamiathis, and Michelangelo Mattei, Titular Archbishop of Hadrianopolis in Haemimonto, serving as co-consecrators.

[1] While bishop, he was the principal consecrator of:[2] and the principal co-consecrator of:[2] This article about an Italian Catholic cardinal is a stub.