Baldassarre Bonifacio (5 January 1585 – 17 November 1659) was an Italian Catholic bishop, theologian, scholar and historian, known for his work De archivis liber singularis (1632), the first known treatise on the management of archives.

[4] Sometime within the next five years, Bonifacio accompanied Count Girolamo di Porzia, bishop of Adria and papal nuncio, to Germany as a private secretary.

Before his return Pope Urban VIII, upon the recommendation of the Venetian Senate, named him to the bishopric of Hierapetra and Sitia on the Greek island of Crete.

Bonifacio published also a collection of Latin poems (1619) and an essay on ancient Roman historiography, De Romanæ Historiae Scriptoribus excerpta ex Bodino Vossio et aliis, Venice, 1627.

Throughout his life Bonifacio maintained friendly relationships with numerous intellectuals of his day and was a member of several academies (Umoristi, Incogniti, Olimpici, Filarmonici).

[10] Despite having been her friend and protector, in 1621 Bonifacio published the philosophical pamphlet Dell'Immortalità dell'anima, a frontal attack on Sara, whom he repeatedly accused of denying the immortality of the soul.