After completing the middle school of commerce, Dvarionas worked as an organist and conductor of the Youth Choir of Lithuanian Society in Liepāja.

In 1920, Dvarionas went to Leipzig, where he studied piano under Robert Teichmüller at the Conservatory and attended special music theory and composition courses held by Stephan Krehl and Sigfrid Karg-Elert.

After graduating from the Conservatory in 1924, Dvarionas returned to Kaunas, Lithuania where he performed his first recital, and afterwards spent two years studying piano in Berlin under Egon Petri, a famous German pianist.

Dvarionas' final public performance was on May 12, 1972, with the Lithuanian Chamber Orchestra at the Philharmonic Hall; he played a Mozart piano concerto and conducted a mass by Schubert.

The music by Dvarionas may seem extemporaneous, but is natural and rhythmically flexible, and makes an impression of clear and colourful mood.

The composer said of his style in 1971: "My aesthetic ideals were formed under the influence of 19th century romanticism, and I believe in the musician's vocational call to spread beauty, good, harmony, to educate people and to raise them above the routine.