Banco Patagonia is an Argentine commercial bank headquartered in Buenos Aires, and has 200 service points located in the main cities and capitals of the provinces of Argentina.

The first group of shareholders included the brothers Jorge and Ricardo Stuart Milne and Emilio González Moreno.

Mildes grew with the 1996 acquisition of the newly privatized Banco de Río Negro, and was renamed after the latter province's region of Patagonia, in 2000.

Patagonia acquired the insolvent Banco Sudameris (whose portfolio included the Caja de Ahorro, the nation's largest savings and loan), in 2003.

Absorbing Lloyds TSB's Argentine operations in 2004, it grew to become one of the 15 largest banks in Argentina and has branches in Brazil and Uruguay.