[4][5] In 1920, led by its new chairman Maurice Despret [fr], the Banque de Bruxelles established the Crédit General du Congo (also known as Crégéco), legally registered in Léopoldville with administrative headquarters (French: siège administratif) at Rue Royale 66 in Brussels.

[8] Following the initial public offering of the new entity's share, Brufina held 71 percent of the Banque de Bruxelles's equity.

[1]: 53  In 1937, Brufina in turn fell under the control of Belgian businessman Paul de Launoit [nl] through his holding company the Compagnie financière et industrielle (Cofinindus).

[12]: 12 The bank expanded its Belgian branch network in the 1960s, in competition with established incumbents the Générale de Banque in Wallonia and Kredietbank in Flanders.

[12]: 8 In October 1969, Brufina sold part of its residual stake in Banque de Bruxelles to Algemene Bank Nederland (ABN), then repurchased some of it following a political backlash.