[1][2][3] Several places of interest lie along the Rue Royale, for instance the BELvue Museum, Brussels Park, the Congress Column, the Hotel Astoria, the Botanical Garden of Brussels, Le Botanique concert hall and Saint Mary's Royal Church.

In addition, many companies have offices on the street, for instance Accenture and BNP Paribas Fortis, as well as the French-speaking Community of Belgium.

From 1822, the street was extended to the Schaerbeek Gate on the current Small Ring by the engineer Jean-Alexandre Werry and the architect Hendrik Partoes.

Shortly afterwards, it was extended even further on the territory of Saint-Josse-ten-Noode to the newly constructed Place de la Reine/Koninginplein in Schaerbeek, where Saint Mary's Royal Church closes the kilometre-long perspective.

In November 1902, King Leopold II was attacked by the Italian anarchist Gennaro Rubino on the Rue Royale and escaped death.