[3] At least a portion of the Hamdan sent a deputation, led by the poet Malik ibn Namat and the prince Abu Thawr Dhu'l-Mashar, to the Islamic prophet Muhammad in 631 seeking an alliance with him.

The tribe largely remained loyal to the early Muslim state during the Ridda wars which broke out following Muhammad's death in 632.

[1] The Hamdani soldiers who settled in Kufa during and after the Muslim conquest of Iraq became fervent supporters of Ali during his caliphate in 656–661, and his sons Hasan and Husayn after him.

The Hatim family, which led the Yam, established the Isma'ili Hamdanid dynasty at Sanaa at the turn of the 12th century, in rivalry to the Sulayhids.

Banu Al-Mashrouki settled in Lebanon producing well known Maronite influential families such as the Awwad, Massa'ad, Al-Sema'ani, Hasroun.