Baptism of Christ is a 1608–1614 painting by El Greco, made towards the end of his life in Toledo and completed by his son Jorge Manuel Theotocópuli.

Jesus appears kneeling while Saint John the Baptist at right pours water onto his head from a conch.

This large canvas was delivered to the Tavera Hospital shortly before 1624, the date on which it was already included in the inventory of this institution.

It is likely that it was designed to be placed in the main altarpiece, in the central niche of the lower floor, which has the appropriate measurements.

After a brief move, it was returned to the same altarpiece and a landscape was added at the bottom, in order to fill the space that was empty (circa 1670).