Her father was also a cartoonist and he was the creator of the comic strip Luther which was in circulation from 1970 to 1986 under the Los Angeles Times Syndicate newspapers.
[3] While she was still a baby, her family moved to a predominantly Black neighborhood located in New Cassel, New York.
She also created illustrations for The Crisis, published by the NAACP; as well as for The Village Voice and MCA Records.
[3][10] The comic strip traces the experiences of about twelve African-American women[3][5] and gives insight into the challenges of being an African American woman living in the United States.
[3][7] It appeared in newspapers throughout the United States, including Essence, The Sacramento Bee, The Atlanta Journal-Constitution and The Baltimore Sun, as well as in The Gleaner in Jamaica and the Johannesburg Drum magazine.
[11][13] Brandon-Croft's and her father's work are both represented in the Library of Congress and in editions of Best Editorial Cartoons of the Year.