[4] Crampton made her television debut on the daytime drama Days of Our Lives (1983–84) before a supporting role as Leanna Love on the soap opera The Young and the Restless (1987–93, 1998–2002, 2006–07 & 2023).

Later in her career, she would appear in television horror anthologies such as Syfy's Channel Zero: The Dream Door (2018), Hulu's Into the Dark (2019), and Shudder's Creepshow (2021).

[8][better source needed] From New York, Crampton moved to Los Angeles and made her television debut on the daytime drama Days of Our Lives, playing Trista Evans Bradford.

[9] In 1986, Crampton portrayed Suzie Lynn in Chopping Mall, Dr. Katherine McMichaels in From Beyond, and Anne White in Prince of Bel Air.

That year she also guest starred on Civil Wars and portrayed Mindy Lewis on Guiding Light from 1993 to 1995 and left when her contract expired and when she got engaged to L.A.-based actor and director Kristoffer Tabori in April 1995.

In 2001, Crampton had a recurring role as Dr. Leslie Bogan in 5 episodes of the television series Spyder Games and starred in the movie Thy Neighbor's Wife.

The same year, she voiced serial killer Nicolette Aster in an audio drama adaptation of Our Lady of the Inferno[21] and appeared in the Lovecraftian film Sacrifice.

[24] As of 2015, Crampton lives in Mill Valley, California, with her husband, financial executive Robert Bleckman, her two children, and her adult stepson.

[25] Crampton was featured in the asymmetrical horror game The Texas Chain Saw Massacre as a playable character Virginia who used her likeness and voice.