She finished her postgraduate studies in library and information science in 1974; two years later she received a doctorate at the Institute of History, Adam Mickiewicz University in Poznań.
In 1996 she began working as a bibliographer for another database project, the Retrospective Index to Music Periodicals (Répertoire International de la Presse Musicale; RIPM), and by 2000 she fully indexed five Polish music periodicals published during the 19th century (Echo Muzyczne, 1879-1882; Ruch Muzyczny, 1857-1862; Tygodnik Muzyczny, 1820-1821; Pamiętnik Muzyczny Warszawski, 1835-1836; and Gazeta Muzyczna i Teatralna, 1865-1866).
Zakrzewska-Nikiporczyk became the librarian at the University of Southern California's Polish Music Center in 1998, where she catalogued the collections as a Kościuszko Foundation Fellow.
As a musicologist and librarian, Zakrzewska-Nikiporczyk has published 5 books and 68 articles, including her doctoral dissertation about music in Poland from 1870 to 1918.
Zakrzewska-Nikiporczyk received an award at the Young Polish Composers Competition in 1970 for her vocal work A Ave.[6] Her other compositions include:[6]