Hamadou was a member of the Afar ethnic group[1][4] and was born in Tew'o, Dikhil Region, in the southwest of Djibouti.

Hamadou remained prime minister in this government and was additionally assigned the development portfolio.

[12][13] On the night of 9 March 2000, Hamadou was admitted to the French army hospital in Djibouti due to heart trouble.

Although he was re-elected as vice-president of the RPP in early 2001,[1] he subsequently submitted his resignation as prime minister to President Guelleh on 6 February 2001 due to poor health.

[16] Hamadou later resigned as RPP vice-president due to his health and was succeeded in that post by Dileita on 3 July 2003.