Barreteros was founded in the semi-pro league Liga Nacional de Clubes achieving two championships in 2001 and 2003, in 2004 they started playing in LNBP taking the place of Chihuahua Dorados.

[1] The first season of Barreteros in pro basketball was also their best, as they eliminated Algodoneros de la Comarca in the first round of playoffs.

In 2005 Zacatecas was eliminated by the heavily favoured and eventual champions Halcones UV Xalapa in three games on the first round of playoffs.

In 2009 Barreteros made the playoffs but was eliminated by regional rivals Panteras Aguascalientes.

In 2010, it was announced that the team would not take part in that year's season, causing great discontent among fans and leaving the state without a professional sports franchise for the first time in more than a decade.