[2] Griffith joined Muhammad Mohiuddin's MD Xenoheart laboratory in 2018.

Together, they were able to demonstrate that the heart of a genetically altered pig could support life when transplanted into an orthotopic position in the chest for up to 9 months.

Griffith and Mohiuddin performed the first successful xenotransplantation of a genetically modified pig heart to a human on January 7, 2022.

[5] On September 20, 2023, Bartley P. Griffith performed his second pig heart transplant.

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