Bartolomeu Perestrello (Portuguese pronunciation: [baɾtuluˈmew pɨɾɨʃˈtɾelu], in Italian Bartolomeo Perestrello), 1st Capitão Donatário, Lord and Governor of the Island of Porto Santo (c. 1395 – 1457) was a Portuguese navigator and explorer that is claimed to have discovered and populated Porto Santo Island (1419) together with João Gonçalves Zarco and Tristão Vaz Teixeira.
One of his daughters, Filipa Moniz Perestrelo (born c. 1455), around 1479 married Christopher Columbus,[2] who lived in Madeira and Porto Santo.
He married four times, firstly to Margarida Martins, without known issue, secondly with Branca Dias, fathering Branca Dias Perestrello, lady-in-waiting to Eleanor of Aragon, Queen of Portugal, and mistress of Dom Pedro de Noronha (Castle of Gijón, 1379 – August 20, 1452), 4th Archbishop of Lisbon (1424–1452), by whom she had issue, including D. Pedro de Noronha, Lord Chamberlain to King John II of Portugal.
Thirdly in 1446 to Brites Furtado de Mendonça, (aunt of King John II's mistress Ana de Mendonça) and had issue including Izeu Perestrelo, wife of Pedro Correia, First Captain of Graciosa Island in the Azores and one of King John II's twenty-five bodyguards.
He also had two sisters: Catarina Perestrello, married to Aires Anes de Beja, Escrivão da Puridade (a Secretary) of John I of Portugal.