The responsible transport authorities are the Swiss cantons of Basel-City, Basel-Country, Aargau, Solothurn, Jura; the German state of Baden-Württemberg and the French region of Grand Est.

Lines S1 (between Basel SBB and Stein-Säckingen) and S3 (between Olten and Laufen) with a large patronage run every half hour.

Lines with low ridership (S1 between Stein-Säckingen and Laufenburg/Frick, S3 between Laufen and Porrentruy and S9) operate at hourly intervals.

Line RB27 and RB30 are operated by DB Regio, the commuter rail arm of Deutsche Bahn, and both serve Switzerland and Germany.

The 357 km-long railway network currently includes 108 stations and stops, of which 47 are in Switzerland, 54 in Germany and 7 are in France.