[3] The campaign to designate Basin and Range as a national monument had the support of Nevada's largest employer, MGM Resorts International, as well as Wynn Resorts, Barrick Gold Corporation, Rockwood Lithium North America, the Las Vegas Metro Chamber of Commerce, and the Las Vegas Convention and Visitors Authority.

[1][5] The Sierra Club also praised the designation, stating that the area was "a fitting addition to our protected public lands" because it is "one of the best examples of the spectacular basins framed by Nevada's breathtaking mountain ranges, a resting place for historic artifacts critical to understanding our nation's Native American cultural history, and home to unique plants and animals, some found only in Nevada and this region.

[8] The Basin and Range National Monument area has geological, ecological, cultural, historical, paleoecological, seismological, archaeological, and paleoclimatological significance.

[1] Within the monument boundary there are privately owned lands including Michael Heizer's City, a massive earth art piece similar in size to the National Mall in Washington.

[1] Fauna of significance in the national monument include desert bighorn sheep, golden eagle, and many species of bat, lizard, and snake.