King, The Beach Boys, Big & Rich, Collective Soul, Hootie & the Blowfish, Keith Urban, LeAnn Rimes, Ludacris, The Temptations, Travis Tritt, Stone Temple Pilots, Uncle Kracker, and Velvet Revolver have performed at BayFest.

Bayfest 2010 took place from October 1-3, 2010 and the lineup included: Godsmack, Shinedown, Mötley Crüe, Nelly, Five Finger Death Punch, Saving Abel, Lady Antebellum, Adelitas Way, Papa Roach, Sick Puppies, Skillet, Fuel, Tonic, Rehab, Earth, Wind & Fire, and Grayson Capps, Evans Blue Bayfest 2009 took place from October 2-4, 2009 and the lineup included: Stone Temple Pilots, 3 Doors Down, Steve Miller Band, Train, Ludacris, Chevelle, Cage the Elephant, Cavo, Halestorm, Pop Evil, and Meat Puppets.

Bayfest 2008 took place from October 3-5, 2008 and the lineup included: Darius Rucker, Kid Rock, Three Days Grace, Candlebox, Eric Church, Nelly, Blake Shelton, Better Than Ezra, David Nail, Sister Hazel, Saving Abel, Puddle of Mudd, P.O.D., and Bow Wow.

Bayfest 2007 took place from October 5-7, 2007 and the lineup included: Velvet Revolver, Alice in Chains, Blue Öyster Cult, Big & Rich, LeAnn Rimes, Ludacris, Daughtry, Hellyeah, Flyleaf, John Miller, Luke Bryan, Willie Clayton, Joan Jett and the Blackhearts, Sparta, Operator, The S.O.S.

Bayfest 2006 took place from October 6-8, 2006 and the lineup included: Lynyrd Skynyrd, Gretchen Wilson, MC Hammer, Keith Anderson, Shinedown, Evans Blue, 10 Years, Al Green, Michael Bolton, Gary Allan, Trick Pony, Hinder, Blaine Larsen, and The Wreckers.

Bayfest 2005 took place from October 7-9, 2005 and the lineup included: Widespread Panic, Grand Funk Railroad, Jason Aldean, The Grass Roots, Hot Apple Pie, Craig Morgan, Dark New Day, Elvin Bishop, The Lowdown, Kool & the Gang, and Adam Holt & The Blues Congregation.

Bayfest 2004 took place from October 1-3, 2004 and the lineup included: The Beach Boys, The Charlie Daniels Band, Travis Tritt, Collective Soul, Three Days Grace, Breaking Benjamin, Seether, Uncle Kracker, Ruben Studdard, George Clinton & Parliament Funkadelic, Josh Turner, John Miller, Brad Cotter, Regina Belle, Buddy Jewell, The Commodores, Will Downing, Andy Smith, Dr. Hook, Edwin McCain, Emerson Drive, The Movement, Debbie 'The Delta Diva' Bivens and Dennis Nelson.