Her films include The Seven Deadly Sins (1990), The Almost True Story of Pepita the Gunslinger (1992), In This Tricky Life (2001), and Masangeles (2008).

In 1992 she directed the film The Almost True Story of Pepita the Gunslinger (original Spanish title: La historia casi verdadera de Pepita la Pistolera), which set a standard in Uruguayan cinema and won several awards.

Between 1998 and 2001 she wrote and directed In This Tricky Life (original Spanish title: En la puta vida,[2] a Uruguayan/Belgian/Spanish/Cuban co-production.

The movie premiered in 2001 and became the biggest box office success in the history of Uruguayan cinema.

International awards received by Flores Silva's movies: Masangeles (2008): In This Tricky Life (2001): The Almost True Story of Pepita the Gunslinger (1992):