Beatriz was born in Medina del Campo to the powerful and wealthy Bobadilla family with close ties to the Crown of Castile.
Her father, Juan de Bobadilla, held numerous roles including alderman for Medina del Campo, governor of Madrid, and chief huntsman for the Catholic Monarchs.
As a result of the former, Queen Isabella arranged for her to marry Hernán (also known as Fernán) Peraza, Lord of La Gomera and El Hierro, in 1482.
However, there were a number of uprisings by the Guanches aboriginals due to outrages committed by the rulers on the native Gomeros.
Beatriz de Bobadilla y Ossorio, the Countess of La Gomera and widow of Hernán Peraza the Younger, offered him vital support in preparations of the fleet and he ended up staying one month.