Bedfordshire and Milton Keynes was a constituency of the European Parliament located in the United Kingdom, electing one Member of the European Parliament by the first-past-the-post electoral system.

Created in 1994 from parts of Cambridge and Bedfordshire North and Suffolk, it was abolished in 1999 on the adoption of proportional representation for European elections in Great Britain.

It was mostly succeeded by the East of England region, with the remaining part succeeded by the South East England region.

It consisted of the parliamentary constituencies of Luton North, Luton South, Mid Bedfordshire, Milton Keynes South West, North Bedfordshire, North East Milton Keynes and South West Bedfordshire.

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