The hotel is located two blocks from the Plaza de Armas, in the former premises of Saint Anthony the Abbot Seminary.

In keeping with the decrees of the Council of Trent regarding the training of the clergy, in 1598 Antonio de Raya y Navarrete, the Bishop of Cusco, founded Saint Anthony the Abbot Seminary and entrusted its administration to the Jesuits.

Its purpose was to provide training to young men who wanted to serve the Church, especially the sons of impoverished conquistadores.

[2] In the mid-20th century, the Jesuits obtained the financial support of Cardinal Richard Cushing, the Archbishop of Boston, for the building of a new seminary.

Hotel Monasterio was obtained by the Sousa group after the privatization process of Entur Peru during 1994 and it opened its doors in the CADE of 1995.