He is best known as the creator and executive producer of the Cartoon Network animated series The Amazing World of Gumball.

His idea was a show called Gumball about reject cartoon characters attending a remedial school, but producers felt this concept was too sad.

The producers liked this idea, and work went underway for what would become The Amazing World of Gumball, which premiered on Cartoon Network on May 3, 2011.

Following the series finale of The Amazing World of Gumball, and the mixed reviews it received from fans, Bocquelet said that he would create a film to resolve its cliffhanger.

[6] On September 21, 2021, HBO Max and Cartoon Network announced the film had been greenlit and was now titled The Amazing World of Gumball: The Movie!.