When Kweller turned eight, someone showed him how to play "Heart and Soul" on the piano, and the youngster immediately began to create his own songs using the same chords.

By the time he was nine, he had a dozen original compositions under his belt and had entered a songwriting contest sponsored by Billboard magazine, where he won an honorable mention.

[4] In 1993, Kweller became friends with a local musician, drummer John Kent, and formed the band Radish with bassist Ryan Green.

After an unexpected bidding war for Dizzy, Radish signed to Mercury Records to release the full-length Restraining Bolt.

The band went on multiple European tours, including opening slots for Faith No More and Main Stage at Reading Festival in 1997.

In 1998, Radish became a quartet; it featured Joe Butcher of the Polyphonic Spree and UFOFU on lead guitar and Debbie Williams on bass.

Radish went to Muscle Shoals Studio in Alabama to record the follow-up to Restraining Bolt, provisionally titled Discount Fireworks.

While mastering Discount Fireworks in New York City, Kweller and Kent met bassist Josh Lattanzi, who would become Radish's fifth and final bass player.

The album featured John Kent on drums and Josh Lattanzi on bass, and showcased a wide variety of sound from quirky pop, to folk, to punk.

To support the release of the album and EP, he put together a live band, initially composed of Lattanzi on bass, Fred Eltringham on drums, and Mike Stroud on guitar and keyboards.

Late in 2003, Kweller provided lead vocals on the song "I Hope Tomorrow is Like Today" from Guster's album Keep It Together.

[8] By this point, the lineup of his live band had changed to include John Kent on drums and Jason Roberts on guitar and keyboards, after Mike Stroud left to concentrate on his own band Ratatat and Fred Eltringham left to play drums in The Wallflowers.

Kweller's fifth studio album, Go Fly a Kite, was his first release produced solely by his own record label, The Noise Company.

On January 22, 2019, Kweller announced his return to music after he and his family had a near-death experience after carbon monoxide poisoning during a vacation in New Mexico.

[13] Kweller's music video for Heart Attack Kid, was made in collaboration with Robert Strange of Superorganism and released on February 19, 2019.

The Noise Company (record label) has said the album is a priority of theirs in 2022, starting with a radio campaign for the single "American Cigarettes" in early 2022.

As part of his 2006 tour, Kweller played the Austin City Limits, where he was plagued by a severe nosebleed for the entirety of his set.

After covering his guitar in blood, he attempted to stop the flow by inserting a travel-size tampon thrown onto the stage by a fan, which expanded painfully during a performance of "This Is War".

After attempting to play "Falling" at a piano which he also covered in blood, Kweller was forced to end the set early.

This time, he did not get a bloody nose; however, commemorative T-shirts were sold at the merchandise booth with fake blood stains that said "ACL 2007: The return of Ben Kweller".