[2] He was educated at Rome under the tutelage of his maternal uncle, Francesco Ubaldi Baldeschi, Auditor of the Roman Rota.
[4] He studied literature in Perugia at the seminary and the College of S. Bernardo, under Alfonso Alessandri and Marco Antonio Bonciario.
His reputation grew to such an extent that the College of Advocates of Perugia elected him a member of their body on 27 March 1626.
[8] On 28 November 1633, Pope Urban VIII named Benedetto Monaldi Baldeschi a cardinal, and on 9 January 1634 he was assigned the Deaconry of Ss.
[11] On 23 Apr 1634, he was consecrated bishop by Antonio Marcello Barberini, Cardinal-Priest of Sant'Onofrio, with Faustus Poli, Titular Archbishop of Amasea, and Celso Zani, Bishop Emeritus of Città della Pieve, serving as co-consecrators.
[12] To govern his diocese of Perugia while he was absent as Legate in Bologna, he appointed his brother Orazio Monaldi as his Vicar General.
He did not make his own solemn entry into the diocese until 18 July 1637, and he departed for Rome in November, not returning until Lent of 1638.