The college was established in February, 1953 as a Government institution with the motto PER ARDUA AD ASTRA (Through the Sky to the Star).
Nana Yiadom Boakye Owusu II, the then Omanhene of Berekum traditional area released 42hectares (103.491 acres) of land, and laid the foundation stone for the establishment of the college.
Berekum Girls Secondary school was established in 1972, and attached to the college, which became a female institution.
Men were re-admitted into the college in 1974 which rendered the Girls Secondary School removed in 1975.
The college has seen impressive academic record over the years and have trained about eight thousand teachers, a good number of whom have served or are serving in other capacities as public servants, lawyers, accountants, lecturers, politicians, business executives, traditional rulers and media practitioners.
[4] Berekum college places emphasis on discipline, maintenance of plants and structures, and environmental cleanliness.
The Government of Ghana with assistance from Kreditantstallt FÜr Wiederaufbau (KfW) completed some major rehabilitation and constructional works in the college in July, 2000.
Under the GETFund, the college has been provided with a modern one-storey Library Complex as well as a 12-Unit Classroom Block.