Beren Saat made her acting debut with a minor part in the television series Aşkımızda Ölüm Var (2004).
She starred as a feisty tomboy named Yasemin Ünsal in the ATV's political series Hatırla Sevgili (2006–2008) and came to international attention for her role as Bihter Yöreoğlu Ziyagil, an unfaithful wife, in the Kanal D's romantic series Aşk-ı Memnu (2008–2010), for which she received critical acclaim and won numerous accolades, including two Golden Butterfly Awards.
Her other major roles in television includes a rape victim, Fatmagül Ketenci Ilgaz, in the social drama Fatmagül'ün Suçu Ne?
[9] In 2004, she was cast as Nermin in the TV series Aşkımızda Ölüm Var, directed by Nazif Tunç and Ümit Efekan.
[10] In 2005, she starred as the female lead Zilan Şahvar Azizoğlu in Aşka Sürgün which was produced by Tomris Giritlioğlu and directed by Cemal Şan.
[11] In 2006, she was cast as Yasemin Ünsal in the popular series Hatırla Sevgili directed by Faruk Teber and Ümmü Burha.
The series focused on the political events occurred during 1950–70 and Saat achieved great success and nationwide fame during the period of its broadcast.
[15] Later in 2008, she was cast in a leading role as Bihter Yöreoğlu Ziyagil in Aşk-ı Memnu (Forbidden Love), a romantic drama series which was adapted from author Halid Ziya Uşaklıgil's novel of the same name.
[16] The story is about a girl, Bihter Yöreoğlu Ziyagil, who falls in a forbidden love with her husband's young nephew, Behlül (portrayed by Kıvanç Tatlıtuğ).
Aşk-ı Memnu received positive response from the audience and was the most watched TV series in the history of Turkish television productions.
[20][21] After the show was broadcast around the world, Saat rose to international prominence specially in the Middle East and Europe.
[23] The series also reached great popularity in Egypt and a TV channel made a documentary about Beren Saat's life.
Hamdi Alkan, a member of Türkiye'nin Yıldızları jury was interviewed and detailed information about Beren Saat.
[24] At the end of 2010, Media Monitoring Center after a research announced that Saat has been one of the most popular TV series actors and the most talked actress of the year.
Co-starred with Murat Yıldırım, Okan Yalabık and Belçim Bilgin, Saat portrayed the Greek prostitute Elena.
[52] The starring cast included Mert Fırat, Yiğit Özşener, Zafer Algöz, Arzu Gamze Kılınç and Engin Hepileri.
Other co-stars included Ayça Bingöl, Turgay Kantürk and Hazar Ergüçlü as well as the child actress Melis Mutluç.
[55] After her role in this film, an American website named Beren Saat as one of the "stars" in the world and said the characters that were shown in the adapted movie were portrayed better than the original one.
The show's producer Timur Savcı refuted these allegations and said that the person who was chosen to portray Kösem Sultan would remain unrecognized.
Between 2019 and 2021, Saat starred in the Netflix original series The Gift, in which she portrayed the lead role Atiye, an artist who comes across universal secrets in Anatolia.
[63] Writing for Hürriyet, Onur Baştürk mentioned that there was "no trace of the childishness or disharmony" that he had seen in The Protector, and praised the performance of all the actors, including Saat and her co-star Mehmet Günsür.
[67] Saat and Doğulu became engaged on 23 February 2014 in Istanbul[68] and were married on 29 July 2014 in a private ceremony in Los Angeles, California in the United States.
[71][72] In December of the same year, she appeared on a calendar that was made and designed by Trendus.com, with a girl suffering from leukemia with Snow White costume on its cover.
[75] In September 2014, Saat vocalized in "Baba Beni Okula Gönder" (Daddy Send Me to School) campaign's advertising film directed by Ozan Açıktan.
[77] In the same month, Saat along with many other celebrities participated in "Gençliğe Hitabe" program for addressing young people with hearing disabilities using sign language.