[1] Its county seat is Moncks Corner, and the largest community is Goose Creek.

[3] Berkeley County is included in the Charleston-North Charleston, SC Metropolitan Statistical Area.

It was named after John and William Berkeley, co-owners of the Province of Carolina.

It did not exist as a District during most of the 19th century and generally was part of the Low Country culture.

In 1882, after Democrats regained control of the state legislature following the Reconstruction era, they established the current incarnation of Berkeley County, with its seat at Mount Pleasant.

The Old Berkeley County Courthouse was listed on the National Register of Historic Places in 1971.

At the 2010 census, there were 177,843 people, 65,419 households, and 47,141 families living in the county.

[17] At the 2000 census, there were 142,651 people, 49,922 households, and 37,691 families living in the county.

County government (as of 2023):[19] Berkeley County Council: Other Elected Officials: In 2020, Joe Biden received 43.3% of the vote, the best performance for a Democrat since Jimmy Carter in 1976.

[23] As of April 2024[update], some of the largest employers in the county include Blackbaud, Booz Allen Hamilton, Nucor, Publix, Volvo Cars, and Walmart.