She replaced chancellor Robert Hemenway in August 2009,[2][3] and retired in June 2017.

As part of a Fulbright Foundation fellowship, she conducted postdoctoral research in cross-cultural psychology in Denmark.

She has held a number of leadership positions and memberships on a variety of boards and committees, including several with the American Psychological Association.

She also served as a faculty affiliate at the Center for Creative leadership from 1998 to 2004.

On September 22, 2016, Gray-Little announced she would retire at the end of the 2016–17 school year.