Although she was not allowed to pursue an academic career, De Vriese opened a private pediatric clinic and served as the director of the Children's Ward at the Bijloke Hospital in Ghent.

[9] The following year she was awarded a prize and distinction as Laureate in the University Competition, which also earned her a gold medal from the mayor of the city of Ghent.

[7] There was no precedent for a woman to work in a laboratory and Leboucq sought approval from the faculty council, the rector, and the managing inspector from the Education Ministry before consent was given.

[11] In 1905, she obtained her specialist certification in anatomy with the dissertation Recherches sur la morphologie de l'artère basilaire (Research on the morphology of the basilar artery).

After a protracted period of petitioning,[12] De Vriese left Ghent University in 1908 and Leboucq approved the candidacy of his son for the position.

[3] The samples of bones, muscles, and organs that she collected and prepared for study are preserved at the Anatomical Museum of the Department of Basic Medical Sciences.