[6] Wolfe starred as Cathy in the Off-Broadway revival of The Last Five Years, which ran at the Second Stage Theater from March 7, 2013 (previews), to May 18, 2013.

Charles Isherwood, in his review in The New York Times, wrote that Wolfe has "a bright, strong soprano with a keen belt.

The CurtainUp reviewer wrote: "Betsy Wolfe also has little to do as David's girlfriend Ellen but, like Ziemba, when she does get to sing it's lovely.

[11] She appeared in a reading of a new musical titled Flying Over Sunset by James Lapine (book and director), Tom Kitt (score) and Michael Korie (lyrics).

The reading took place at the Vineyard Arts Project in Edgartown, Massachusetts, on July 29, 2016, with additional cast members Marin Mazzie and Boyd Gaines.

In February 2018, Wolfe and Cynthia Rose announced that they would be founding a company, BroadwayEvolved, to give workshops and masterclasses to young actors.

[20][21] In 2016 and 2017, Wolfe appeared with Darren Criss and Adam Kantor, respectively, in The New York Pops' concerts "Best of Broadway" and "Women of Notes: In Dedication to Female Composers and Lyricists" at Carnegie Hall, with appearances by Robert Lopez, Kristen Anderson-Lopez, and Jason Robert Brown, and by Sara Bareilles, Ingrid Michaelson, Georgia Stitt, and Shaina Taub, respectively.

[24] Wolfe appeared in the Metropolitan Opera production of Die Fledermaus as Ida, with a new book by Douglas Carter Beane.