[7][8] In 2015, Edu became the youngest person to be appointed Special Adviser to the Executive Governor of Cross River State Benedict Ayade on Community and Primary Healthcare.
[15][16] In July 2023, President Bola Ahmed Tinubu nominated Betta Edu for minister as the Nigerian senate unveiled the 28 nominees for ministerial appointment.
[19][20] In August 2023, Betta was sworn in as minister of humanitarian affairs and poverty alleviation and the All progressives congress replaced her as National women leader.
[24] The Cross River state chapter of the Nigerian Medical Association passed a vote of no confidence on Edu over accusations of professional misconduct in the context of the COVID-19 pandemic.
[3] On 8 January 2024, she was suspended from her position as the minister of humanitarian affairs and poverty alleviation by President Bola Ahmed Tinubu for allegedly diverting ₦585 million in ministry funds to a personal bank account.
According to a BBC publication the Economic and Financial Crimes Commission had recovered an equivalent of $24million from accounts allegedly linked to Edu.