Her major work is the Tito Amato mystery series set in 18th-century Venice, published by Poisoned Pen Press.

She is also the co-author, with Joanne Dobson, of a stand-alone crime novel set in New York City on the eve of World War II.

Myers' novels are traditional mysteries which feature a large cast of characters, a deep sense of time and place, and meticulously researched period details.

She also completed a residency program in psychiatry and practiced at a public mental health clinic in eastern Kentucky for approximately ten years before taking up writing full-time.

Four stories which have been published in Alfred Hitchcock's Mystery Magazine form a series featuring Nicco Zianni, an 18th-century "Private Eye."