"Big Man on Hippocampus" is the tenth episode of the eighth season of the American animated sitcom Family Guy.
The episode features Peter after he suddenly begins suffering from amnesia, and can no longer remember anything about his life, including his own family and friends.
The two walk home, happy in their reunion, leaving Quagmire as he frustratedly attempts increasingly drastic measures to "resuscitate" his genitalia using: a penis pump, intravenous therapy, and a crash cart with a defibrillator in his closet.
[3] "Big Man on Hippocampus", along with the eleven other episodes from Family Guy's eighth season, was released on a three-disc DVD set in the United States on December 13, 2011.
The sets include brief audio commentaries by various crew and cast members for several episodes, a collection of deleted scenes and animatics, a special mini-feature which discussed the process behind animating "And Then There Were Fewer", a mini-feature entitled "The Comical Adventures of Family Guy – Brian & Stewie: The Lost Phone Call", and footage of the Family Guy panel at the 2010 San Diego Comic-Con.
[7] While filming the movie, Johnson had reached out to MacFarlane, saying that he would love to "return the favor" by appearing on Family Guy, which eventually led to his role in this episode.
Recurring guest voice actors Alexandra Breckenridge and Ralph Garman, along with writers Steve Callaghan, Mark Hentemann, Danny Smith, Alec Sulkin and John Viener, also made minor appearances.
[2] The segment features a re-creation of the game show's original 1976 set and rules, including host Richard Dawson's practice of kissing the female contestants.
As an answer to one of the questions, Peter supplies "the flute that Captain Picard played, first in his imagination, and then in real life, in the episode "The Inner Light" from Star Trek: The Next Generation" (which ironically had sold for $48,000 at a Christie's auction in 2006).
Stewie introduces himself and Brian as Tomax and Xamot respectively and tells Peter they are twins who can feel each other's pain, which is a reference to these characters from the G.I.
[6] At the end of the first act, when Brian says "Oh No", (in place of the commercial interlude from Night Rider) a series of white on black text is shown mocking the apparently tired use of an amnesiac storyline as well as Fox's censorship.
It is a parody of bumpers featured on Cartoon Network's programming block Adult Swim, whose airing of Family Guy contributed to its revival.
Ahsan Haque of IGN praised the "cohesive story" as "[succeeding] on its simplicity," but criticized the series for continuing to broadcast in the 4:3 format, as opposed to widescreen like MacFarlane's other two shows.
[2] Jason Hughes of TV Squad commended the live-action sequence featuring Johnson, as well as the utilization of Meg's personality to create an awkward situation with the family.