The episode centers on Peter as he assumes temporary control of his father-in-law Carter Pewterschmidt's billion-dollar empire after he suffers a heart attack and is in a coma.
Peter immediately becomes power hungry, however, and develops several ridiculous items, prompting Lois and Carter, after he recovers from his coma, to try to trick him into relinquishing control of the company.
[4] On his first day on the job, Peter dismisses the entire board of directors for being unable to keep up with his ideas and hires his friends to manufacture ridiculous items.
Carter confronts Peter in his former office and demands for him to relinquish control of the company, but he refuses; he instead forces him to work as a janitor, have and invite people to his mansion for a Big Bang Theory viewing party, pay a compliment to a sharply dressed Asian man, and clean out the fridge in the employee lounge.
[2] Series regulars Peter Shin and James Purdum served as supervising directors, with Andrew Goldberg and Alex Carter working as staff writers for the episode.
The sets include brief audio commentaries by various crew and cast members for several episodes, a collection of deleted scenes and animatics, a special mini-feature which discussed the process behind animating "And Then There Were Fewer", a mini-feature entitled "The Comical Adventures of Family Guy – Brian & Stewie: The Lost Phone Call", and footage of the Family Guy panel at the 2010 San Diego Comic-Con.
[4] Actors Johnny Galecki and Jim Parsons reprised their roles as Leonard Hofstadter and Sheldon Cooper from The Big Bang Theory respectively.
[2] Recurring guest voice actors Alexandra Breckenridge, Chris Cox, Ralph Garman, Danny Smith, Alec Sulkin and John Viener also made minor appearances.
"[10][11] In introducing new products for Pewterschmidt Industries, Peter decides to create several unorthodox items, which include a cereal line for Jeremy Irons entitled "Jeremy Irons Cereal," a "Scream in a Box," as well as an African American heart rate monitor, which Carter later uses at the hospital, with the system's two settings, Barry White, and Bill Cosby's impersonated voices.
"[4] Jason Hughes of TV Squad also praised the "inside jokes" in the episode, as well as the Scooby-Doo sequence as "a flash of satiric brilliance.
[16] Although it did not name this episode its "Worst TV Show of the Week", the Parents Television Council[17] filed an indecency complaint about "Business Guy" two days after its airdate, citing the lapdance sequence as a possible violation of federal law regarding broadcast decency.