The fifth season of Big Mouth, an American adult animated coming-of-age sitcom created by Andrew Goldberg, Nick Kroll, Mark Levin, and Jennifer Flackett, was released on Netflix on November 5, 2021.

The series centers on teens based on Kroll and Goldberg's upbringing in suburban New York, with Kroll voicing his fictional younger self.

Big Mouth explores puberty while "embrac[ing] a frankness about the human body and sex.

"[1] On Rotten Tomatoes, the fifth season has an approval rating of 100% based on 5 reviews.

[2] On Metacritic, it has a score of 5 out of 0 for the fifth season, based on 1 critic, indicating "universal acclaim".