The Big Stony Railway is a historic intrastate railroad that operated in Virginia.
Located in the southwestern part of the state, it extended from Big Stony Junction on the New River in Giles County to the West Virginia border near Kire.
At the border, it connected with the Interior and West Virginia Railroad, which ran to the Virginia border near Laurel Branch in Monroe County.
The total distance between Big Stony Junction and Potts Creek is approximately 39 miles (63 km).
The remaining 5 miles (8.0 km) of the line are operated as the Potts Valley Branch of Norfolk Southern, and serve a lime plant at Kimballton.